Santos Futebol Clube (Brazilian Portuguese: [ˈsɐ̃tus futʃiˈbɔw ˈklubi] ), commonly known as Santos FC or simply Santos, is a Brazilian sports club based in Vila Belmiro, a bairro in the city of Santos. It is also the team with the most goals in football history. It plays in the Campeonato Paulista, the state of São Paulo's premier state league, as well as the Campeonato Brasileiro Série B, the second tier of the Brazilian football league system, after getting relegated in the 2023 season for the first time in the club's history.

The club was founded in 1912 by the initiative of three sports enthusiasts from Santos by Raimundo Marques, Mário Ferraz de Campos, and Argemiro de Souza Júnior as a response to the lack of representation the city had in football. Since then, Santos has become one of Brazil's most successful clubs, becoming a symbol of O Jogo Bonito (English: The Beautiful Game) in football culture, hence the motto "Técnica e Disciplina" (technique and discipline). This was largely thanks to the club's golden generation of the 1960s, with players like Gilmar, Mauro Ramos, Mengálvio, Coutinho, Pepe, and most notable of all, Pelé, named the "Athlete of the Century" by the International Olympic Committee, and widely regarded as the best and most accomplished footballer in the game's history. Os Santásticos, considered by some the best club team of all times, won a total of 24 titles during that decade including five consecutive league titles, a feat that remains unequaled today. Os Santásticos won four competitions in 1962, thus completing a quadruple, comprising the Campeonato Paulista, the Campeonato Brasileiro Série A, the Copa Libertadores, and the European/South American Cup.

Santos is one of the most successful clubs in the Brasileirão, becoming national champions on eight occasions. It has also won 22 Paulistãos, three Copa Libertadores, two Intercontinental Cups, one Supercopa de Campeones Intercontinentales, one Copa CONMEBOL (the precursor of current Copa Sudamericana), one Copa do Brasil, and one Recopa Sudamericana. On 20 January 1998, Santos became the first team, in any category in the world, to reach the milestone of 10,000 goals in the entire history of football and was voted by FIFA as one of the most successful clubs of the 20th century.

The team plays their home games at the Vila Belmiro, which currently holds up to 20,120 spectators. Santos' regular kit is white shirts, with white shorts, accompanied by white socks. Santos is nicknamed the Peixe (pronounced [ˈpejʃi]; "fish"), in reference to significance of the city's port. The most recognized Santista anthem is the "Leão do Mar" written by Mangeri Neto. In 2013, the club is the 2nd most valuable club in Brazil and South America, and 38th most valuable club in the world according to Brand Finance, worth over $65 million. In terms of revenue, Santos is Brazil's fourth-richest sports club and one of the biggest football clubs in the world, generating an annual turnover of over $114 million in 2012. Santos has many long-standing rivalries, most notably against Corinthians, Palmeiras, and São Paulo.